Re-create membrane in-vivo features

Most of the studies on the cell membrane physiology and biochemical properties are carried out using well-established cell lines. However, results obtained using cell lines may not adequately reproduce the dynamic, metabolism and functional roles of fatty acids and phospholipids observed in animal models or in humans, mainly because their basal biochemical composition considerably differs from that of the original tissues where they supposedly derive.

Martìn V. et al., Journal of Neuroscience Methods, 2006.

Approfondimento

Nowadays, scientists who use cultured cells need more effective and real-like experimental models, that can improve experimental consistency and widen research possibilities, with cell culture technology taking a step forward to become a more useful tool.
Our aim is to help cell culture users in taking this step.
Because of the cultivation method, independently of animal serum use, cultured cells develop a membrane composition that is different from their in-vivo tissue counterparts, therefore widening the differences between experimental models and in-vivo tissue cells.
These differences introduce variability in cell culture models used for scientific research, drug discovery and pre-clinical trials. Remembrane proposes the use of Refeed and Report for cell culture membrane standardisation, aiming at creating more consistent experimental models reflecting the cells actually present in real in-vivo tissues in a more accurate way. By using Remembrane’s products and services, cell culture users will enhance the quality of scientific research, through the use of better experimental models closer to their in-vivo tissue counterparts, that will guarantee more experimental consistency.
This will have a positive impact on the number of necessary experiments or trials, with budget savings as an overall indicator.

Tags:

We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Find out more set your preferences here OK